Drugs often need to cross cell membranes to reach their action targets, which makes a compound's ability to passively cross these cell membranes a critical characteristic to assess. The blood-brain barrier (BBB) is the critical barrier that controls drug exchange in the brain. BBB permeability determination during the early and rapid screening of compounds is essential for drug discovery. The Parallel Artificial Permeability Assay (PAMPA) allows researchers to assess the permeability of test chemicals across the blood-brain barrier quickly and cost-effectively. Creative Biarray's BBB-PAMPA kit offers all the components needed to run a Parallel Artificial Permeability Assay.

 

Donor plate: 1 plate;
Dodecane: 1.5mL;
Acceptor plate: 1 plate;
Dried Lecithin: 1 tube;
High permeability control: 120 uL;
Medium permeability control: 120 uL;
Low permeability control: 120uL.