Cell Expansion Industry Overview

The global cell expansion market size was valued at USD 17.75 billion in 2022 and is expected to register a compound annual growth rate (CAGR) of 12.85% from 2023 to 2030.

The increase in the usage of automated solutions in cell expansion applications is one of the primary market drivers. Automated systems minimize the manpower and costs incurred during the production of Cell Therapy Products (CTP), gene therapies, and other biologics, leading to robust and reliable processes.

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Key players engaged in CTP development are expanding their product lines to address the significant rise in global demand for these therapy products. For instance, in January 2021, Thermo Fisher Scientific introduced the Gibco CTS OpTmizer Pro Serum Free Media platform for developing and expanding human T lymphocytes for cell therapy developers using allogeneic workflows. This platform targets donor cell metabolism, making it suitable for allogeneic, off-the-shelf cell therapies.

The paradigm shift toward Single-Use Systems (SUS) offers substantial production advantages in CTP manufacturing. SUS eliminates concerns of cross-contamination and culture contamination caused due to inappropriate sterilization. SUS also allows the production of CTP with high cell densities and offers cost savings in the long run. Thus, a rise in the adoption of SUS surges the development of CTP, which boosts market growth.

Cellular therapies are constantly gaining popularity in the life sciences industry. A significant rise in funding from private & government organizations and initiatives undertaken by them to encourage the development of cellular therapies act as drivers for the market. The International Society for Stem Cell Research is involved in identifying stem cell-related funding opportunities across biomedical research applications.

Substitution of serum and other incompatible reagents is essential to control the quality of the product in CTP manufacturing. Several research studies have validated that applying serum-free media controls product quality. Researchers have also developed an optimization platform that integrates high-throughput tools with a differential evolution-based algorithm, which acts as an automated effective optimization strategy for serum-free culture formulations. In the third quarter of 2022, Lonza received commercial approval for its two cell and gene therapies, SKYSONA and ZYNTEGLO.

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• The global gene therapy market size was estimated at USD 5.54 billion in 2023 and is projected to grow at a CAGR of 18.88% from 2024 to 2030.
• The global cell therapy market size was estimated at USD 4.74 billion in 2023 and is expected to grow at a compound annual growth rate (CAGR) of 22.66% from 2024 to 2030.

Cell Expansion Market Segmentation

Grand View Research has segmented the global cell expansion market on the basis of product, cell type, application, end-use, and region:

Cell Expansion Product Outlook (Revenue, USD Million, 2018 - 2030)

• Consumables
  • Reagents, Media, & Serum
  • Other Consumables
• Culture Flasks and Accessories
  • Tissue Culture Flasks
  • Bioreactor Accessories
  • Other Culture Flasks and Accessories
• Instruments
  • Automated Cell Expansion Systems
  • Cell Counters
  • Centrifuges
  • Bioreactors
  • Other Instruments

Cell Expansion Cell Type Outlook (Revenue, USD Million, 2018 - 2030)

• Mammalian
• Microbial
• Others

Cell Expansion Application Outlook (Revenue, USD Million, 2018 - 2030)

• Biopharmaceuticals
• Tissue Culture & Engineering
• Vaccine Production
• Drug Development
• Gene Therapy
• Cancer Research
• Stem Cell Research
• Others

Cell Expansion End-use Outlook (Revenue, USD Million, 2018 - 2030)

• Biopharmaceutical & Biotechnology Companies
• Research Institutes
• Cell Banks
• Others

Cell Expansion Regional Outlook (Revenue, USD Million, 2018 - 2030)

• North America
  • US
  • Canada
• Europe
  • UK
  • Germany
  • France
  • Italy
  • Spain
  • Denmark
  • Sweden
  • Norway
• Asia Pacific
  • Japan
  • China
  • India
  • Australia
  • Thailand
  • South Korea
• Latin America
  • Brazil
  • Mexico
  • Argentina
• Middle East and Africa
  • South Africa
  • Saudi Arabia
  • UAE
  • Kuwait

Key Companies profiled:

• Thermo Fisher Scientific, Inc.
• GE Healthcare
• Corning Incorporated
• Merck KGaA
• Miltenyi Biotec
• BD (Becton, Dickinson and Company)
• Terumo BCT, Inc.
• Sartorius AG
• Takara Bio Inc.
• TRINOVA BIOCHEM GmbH
• upcyte technologies GmbH

Key Cell Expansion Company Insights

Key market participants are undertaking several initiatives to expand their market presence and maintain a competitive edge. Moreover, they are involved in collaborations & partnership models, product development, agreements, and business expansion strategies in untapped regions.

For instance, in April 2022, STEMCELL Technologies Canada and Applied Cells Inc. joined forces to develop a modern way to separate cells, through the combination of the MARS platform of Applied Cells with STEMCELL's EasySep kits to make isolating cells from different samples easier and more automatic. These samples can be from whole blood, bone marrow, apheresis products, and tissue. The collaboration aims to improve the process of isolation of cells for research and medical purposes, making it more efficient and effective.

In another development, in May 2023, a research agreement was signed by panCELLa and BioCentriq to study stem cell-derived Natural Killer cell expansion technology. The agreement aims to evaluate panCELLa’s feeder cells, which are genetically engineered, to positively impact the expansion rate, total yield, and potency of manufactured NK cells.

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About Grand View Research

Grand View Research, U.S.-based market research and consulting company, provides syndicated as well as customized research reports and consulting services. Registered in California and headquartered in San Francisco, the company comprises over 425 analysts and consultants, adding more than 1200 market research reports to its vast database each year. These reports offer in-depth analysis on 46 industries across 25 major countries worldwide. With the help of an interactive market intelligence platform, Grand View Research Helps Fortune 500 companies and renowned academic institutes understand the global and regional business environment and gauge the opportunities that lie ahead.